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2022 NFL picks, Super Bowl odds, predictions, best bets from advanced model: This 4-way parlay pays 12-1

The NFL season comes to a close on Sunday when the NFC champion Los Angeles Rams and the AFC champion Cincinnati Bengals square off in the 2022 Super Bowl at SoFi Stadium. Super Bowl 2022 features a quarterback matchup between two former No. 1 overall draft picks: Matthew Stafford of the Rams (who went No. 1 in 2009) and Joe Burrow of the Bengals (2020). Behind Stafford and Burrow, Los Angeles (15-5) and Cincinnati (13-7) both averaged 27.1 points per game during the regular season, which ranked seventh in the league.

When is the Super Bowl 2022? Kickoff is at 6:30 p.m. ET on Sunday. Los Angeles is a four-point favorite in the latest 2022 Super Bowl odds from Caesars Sportsbook, while the over-under is 48.5. Before locking in any 2022 Super Bowl picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model.

The model, which simulates every NFL game 10,000…

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