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Indianapolis Colts at Buffalo Bills (Preseason Game 1) kicks off at 4:00 p.m. ET this Saturday and is available to watch on FOX59 and Colts.com.

Indianapolis Colts at Buffalo Bills (Preseason Game 1) kicks off at 4:00 p.m. ET this Saturday and is available to watch on FOX59 and Colts.com.


The Indianapolis Colts will travel to Buffalo for their 2022 preseason opener. The game time is set for 4:00 p.m. ET on Saturday, August 13 at Highmark Stadium. The contest will mark the 11th preseason matchup between the teams. In their last preseaon contest on Aug. 8, 2019, Buffalo defeated Indianapolis, 24-16.

The Colts finished the 2021 season with a 9-8 record.

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