FAU vs. Charlotte odds, spread, line: 2022 college football picks, Week 0 predictions from model on 43-31 run

The FAU Owls attempt to erase the memory of last year’s poor finish and continue their success in the all-time series when they host the Charlotte 49ers on Saturday in the 2022 season opener for the Conference USA rivals. FAU (5-7, 3-5 CUSA last year) got off to a solid start in 2021, winning five of its first eight games, before closing the campaign with four consecutive losses. One of the Owls’ victories came at Charlotte, where it routed the 49ers 38-9 to improve to 5-2 in the series. Charlotte (5-7, 3-5 in 2021) also ended last season with a thud, losing five of its final six contests – including the last three. Both teams are playing their final campaign in Conference USA before moving to the American Athletic Conference in July 2023.

Kickoff at FAU Stadium in Boca Raton, Fla. is set for 7 p.m. ET on CBS Sports Network. The Owls are 7-point favorites in the latest FAU vs. Charlotte odds from Caesars Sportsbook, while the over/under for total points scored is 59.5. Before making any Charlotte vs. FAU picks and college football predictions, you need to see what the SportsLine Projection Model has to say.

The model simulates every FBS college football game 10,000 times. Over the past six years, the proprietary computer model has generated a stunning profit of almost $3,600 for $100 players on its top-rated college football picks against the spread. It also finished the 2021-22 college football season on a 43-31 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on FAU vs. Charlotte and just locked in its picks and CFB predictions. You can visit SportsLine now to see the model’s picks. Here are the college football odds and betting lines for Charlotte vs. FAU: 

• FAU vs. Charlotte spread: Owls -7 
• FAU vs. Charlotte over/under: 59.5 points 
• FAU vs. Charlotte money line: Owls -280, 49ers +230 
• FAU: The Owls scored 28 or more points in each of their wins last season and fewer than 18 in every loss 
• CHA: The 49ers have recorded both of their wins in the series on the road 
• FAU vs. Charlotte picks: See picks here.