No. 20 Kentucky is ranked in the preseason polls for just the fifth time in school history and for the first time since 1978, so expectations are high for the Wildcats, who finished in second place in the SEC East with a 10-3 record last season. They are going to be without star running back Chris Rodriguez in their opener against Miami (OH) on Saturday night during the Week 1 college football schedule, though. Rodriguez was one of several players suspended indefinitely by head coach Mark Stoops. The Wildcats are still 15-point favorites in the latest Week 1 college football odds at Caesars Sportsbook, while the over/under is set at 54.
Rodriguez ran for 1,379 yards and nine touchdowns last season, and his absence is certainly playing a role in the Week 1 college football spreads. Who should you back in that game, and which other Week 1 college football bets have value? Before locking in any Week 1 college football picks for those games or others, be sure to see the latest college football predictions from SportsLine’s advanced computer model.
The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,600 for $100 players on its top-rated college football picks against the spread. It enters Week 1 of the 2022 college football season on a 45-32 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.
Now, it has turned its attention to the latest Week 1 college football odds from Caesars and locked in picks for every FBS matchup. Head here to see every pick.
Top college football predictions for Week 1
One of the college picks the model is high on in Week 1: Florida (+2.5) covers at home against No. 7 Utah at 7 p.m. ET. The Utes put together a strong 2021 campaign, but they lost two of their first three games before winning nine of 10 down the stretch. They are facing a Florida team that is led by star quarterback Anthony Richardson, who is going to give Utah trouble throughout this game.
First-year head coach Billy Napier brought his top running back and top offensive lineman with him from Louisiana, giving the Gators a nice boost. Utah struggled away from home last year, losing at BYU, at San Diego State and at Oregon State. The Utes are likely going to…
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