College Football

Notre Dame vs. Marshall odds, prediction, spread: 2022 Week 2 college football picks from model on 48-37 run

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The No. 8 Notre Dame Fighting Irish (0-1) and the Marshall Thundering Herd (1-0) clash in a Week 2 battle on Saturday afternoon. The Fighting Irish are hoping to bounce back after falling 21-10 to No. 3 Ohio State in Week 1. Marshall dominated Norfolk State en route to a 55-3 victory in its opener.

Kickoff from Notre Dame Stadium in South Bend, Indiana., is set for 2:30 p.m. ET. Caesars Sportsbook lists the Fighting Irish at -20.5 in the Marshall vs. Notre Dame odds, while the over/under for total points is 50. Before making any Notre Dame vs. Marshall picks, you need to see the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,500 for $100 players on its top-rated college football picks against the spread. It enters Week 2 of the 2022 college football season on a 48-37 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Notre Dame vs. Marshall and just revealed its picks and CFB predictions. You can visit SportsLine now to see the model’s picks. Here are several college football odds and betting lines for Marshall vs. Notre Dame:

  • Notre Dame vs. Marshall spread: Notre Dame -20.5
  • Notre Dame vs. Marshall over/under: 50 points
  • Notre Dame vs. Marshall money line: Fighting Irish -1700, Thundering Herd +950
  • MRSH: Thundering Herd are 5-1 ATS in their last six road games
  • ND: Fighting Irish are 8-1 ATS in their last nine games overall
  • Notre Dame vs. Marshall: See picks at SportsLine

Featured Game | Notre Dame Fighting Irish vs. Marshall Thundering Herd

Why Notre Dame can cover

Notre Dame will be battling in front of its home crowd as the Fighting Irish look to secure their first win of the season. The Fighting Irish offense is led by sophomore quarterback Tyler Buchner. Buchner is a dual-threat who…

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