No. 16 Arkansas opened its season with an impressive win over then-No. 23 Cincinnati last week, but the Razorbacks will have to back up that performance when they host South Carolina on Saturday afternoon during the Week 2 college football schedule. South Carolina got off to a strong start of its own, easily covering the 12.5-point spread in a 35-14 win over Georgia State. The Gamecocks have won the past three meetings against Arkansas, but the Razorbacks hold a 13-10 edge in the all-time series. Caesars Sportsbook has Arkansas listed as an 8.5-point favorite in the latest Week 2 college football odds.
Another SEC showdown in Week 2 pits No. 12 Florida vs. No. 20 Kentucky on Saturday night. The Gators are 5.5-point home favorites in the Week 2 college football spreads, but which team should you back with your Week 2 college football bets? Before locking in any Week 2 college football picks for those games or others, be sure to see the latest college football predictions from SportsLine’s advanced computer model.
The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,500 for $100 players on its top-rated college football picks against the spread. It enters Week 2 of the 2022 college football season on a 48-37 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.
Now, it has turned its attention to the latest Week 2 college football odds from Caesars and locked in picks for every FBS matchup. Head here to see every pick.
Top college football predictions for Week 2
One of the college picks the model is high on in Week 2: The Pittsburgh Panthers (+6) stay within the spread against the Tennessee Volunteers in a 3:30 p.m. ET matchup at Acrisure Stadium in Pittsburgh. Tennessee cruised to a 59-10 win over Ball State last week, but Pittsburgh picked up a win over a quality opponent with its 38-31 victory against West Virginia.
The Panthers are going to be a much stiffer test for Tennessee than what it faced last week, especially considering that Pittsburgh notched a 41-34 win at Neyland Stadium when these teams met last year. Transfer quarterback Kedon Slovis completed 16 of 24 passes for 308 yards and a touchdown against West Virginia, marking the highest…
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