Vanderbilt vs. Northern Illinois odds, line: 2022 college football picks, Week 3 predictions from provenmodel

The Northern Illinois Huskies will be looking for a rare win over a Power Five opponent when they host the Vanderbilt Commodores on Saturday afternoon. Northern Illinois is also trying to bounce back from a 38-35 loss to Tulsa last weekend. Vanderbilt opened the season with wins over Hawaii and Elon before losing to then-No. 23 Wake Forest last week. 

Kickoff is set for 3:30 p.m. ET on CBS Sports Network. The Huskies are favored by 2.5 points in the latest Northern Illinois vs. Vanderbilt odds from Caesars Sportsbook, while the over/under is set at 59.5. Before locking in any Vanderbilt vs. Northern Illinois picks, you’ll want to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,400 for $100 players on its top-rated college football picks against the spread. It enters Week 3 of the 2022 college football season on a 50-41 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Northern Illinois vs. Vanderbilt. You can head to SportsLine to see its picks. Here are several college football odds for Vanderbilt vs. NIU:

• Northern Illinois vs. Vanderbilt spread: Northern Illinois -2.5
• Northern Illinois vs. Vanderbilt over/under: 59.5 points
• Northern Illinois vs. Vanderbilt picks: See picks here

Why Northern Illinois can cover

Northern Illinois escaped with a win over Eastern Illinois as a monster favorite in Week 1, but it played much better on the road against Tulsa last week. The Huskies were unable to hold onto their 35-31 lead in the final minute of the game after erasing a 17-0 first-half deficit. However, they still covered the 6.5-point spread as the underdogs, and motivation will not be an issue against an SEC opponent. 

Senior quarterback Rocky…