The Buffalo Bills look to build on their case as the best team in the NFL on Monday night in Week 2, as they host Derrick Henry and the Tennessee Titans. This is a rematch of an incredible Monday night game that took place last year, when Henry ran for 143 yards and three touchdowns, while Jeffery Simmons stuffed Josh Allen at the goal line on fourth down with just 22 seconds remaining in the fourth quarter.
Fast forward a year and things look very different. The Bills are 1-0 and the Super Bowl favorites, while the Titans no longer have A.J. Brown and are coming off of a tough upset loss to the New York Giants in Week 1. Tennessee may seem destined to take a step backwards from last year, but the Titans are a very tough team to predict. They can lose to the New York Jets one week, and then blow out the eventual Super Bowl champions on the road, just like they did last season. With how wacky Sunday was around the NFL, should we expect the unexpected in Buffalo tonight?
Below, we will break down this matchup from a gambling perspective and examine the line movement, Over/Under and player props to consider. First, here’s how you can watch Monday’s matchup.
All NFL odds are via Caesars Sportsbook.
How to watch
Date: Monday, Sept. 19 | Time: 8:15 p.m. ET
Location: Highmark Stadium (Orchard Park, New York)
TV: ESPN | Stream: fuboTV (click here)
Follow: CBS Sports App
Odds: Bills -10, O/U 47.5
Injury report
Line movement
Latest Odds:
Buffalo Bills
-10
The Bills opened up as 7.5-point favorites on Monday, May 16. After the Titans’ Week 1 loss, the line reopened at BUF -9.5 last Sunday night. The next day, it rose to BUF -10, where it has remained.
The pick: Bills -10. In my Week 2 picks column, I took the Bills to win, but the Titans to cover. It’s easy to make an argument for a solid road dog to cover a double-digit spread, but a…
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