West Virginia vs. Virginia Tech odds, prediction: 2022 Week 4 college football picks from model on 51-43 run

The West Virginia Mountaineers look to get to the .500 mark when they visit the Virginia Tech Hokies on Thursday. West Virginia (1-2) lost its first two games of the 2022 season but took out its frustrations against Towson on Saturday as the Mountaineers cruised to a 65-7 victory. Virginia Tech (2-1) is coming off its second straight win, a 27-7 triumph over Wofford. The Mountaineers posted a 27-21 home victory against the Hokies last season to improve to 29-23-1 in the all-time series.

Kickoff at Lane Stadium in Blacksburg, Va., is set for 7:30 p.m. ET. The Mountaineers are 1.5-point favorites in the latest West Virginia vs. Virginia Tech odds from Caesars Sportsbook, while the over/under for total points scored is 50.5. Before making any Virginia Tech vs. West Virginia picks, you need to see the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,300 for $100 players on its top-rated college football picks against the spread. It enters Week 4 of the 2022 college football season on a 51-43 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on West Virginia vs. Virginia Tech and just locked in its picks and CFB predictions. You can visit SportsLine now to see the model’s picks. Here are the college football odds and betting lines for Virginia Tech vs. West Virginia: 

• West Virginia vs. Virginia Tech spread: Mountaineers -1.5 
• West Virginia vs. Virginia Tech over/under: 50.5 points 
• West Virginia vs. Virginia Tech money line: Mountaineers -110, Hokies -110
• WVU: The Mountaineers are 4-1 against the spread in their last five non-conference games 
• VT: The Hokies are 1-11 ATS in their last 12 contests following a straight-up win 
• West Virginia vs. Virginia Tech picks: See picks here