What to watch for: Several league leaders through two weeks will be on the field Sunday. Wide receivers Tyreek Hill (284 yards), Stefon Diggs (270 yards) and Jaylen Waddle (240 yards) are the NFL’s three leading receivers, catching passes from the league’s leading and fourth-leading passers, respectively, in the Dolphins’ Tua Tagovailoa (739 passing yards) and the Bills’ Josh Allen (614 passing yards). And on the defensive side of things, Bills safety Jordan Poyer is one of five players with multiple interceptions this season. — Marcel Louis-Jacques
Bold prediction: Allen will throw for at least 325 yards and five touchdown passes, continuing his impressive streak of success against the Dolphins (19 passing touchdowns, four rushing touchdowns and three turnovers in his past seven games vs. Miami). The Dolphins’ defense has struggled this season against the pass, giving up a league-high 9.0 yards per passing attempt and a 71.2% completion percentage (28th). Allen leads the NFL in Total QBR (87.1) and should have no problem taking advantage. — Alaina Getzenberg
Stat to know: Since the start of last season, no defense has been better at taking away the deep ball than the Bills. Over that span, Buffalo ranks first in opponent QBR and opponent completions, and it hasn’t allowed a single touchdown on passes thrown 20-plus yards downfield. But Tagovailoa threw two such TDs in Week 2.
Betting nugget: Buffalo is 6-1-1 ATS in its past eight division games, but Miami is 10-4-1 ATS in its past 15 division games.
Moody’s prediction: Bills 31, Dolphins 27
Walder’s prediction: Bills 30, Dolphins 23
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