College Football

Clemson vs. North Carolina State prediction, odds: 2022 Week 5 college football picks, best bets by top model

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The fifth-ranked Clemson Tigers will look to tie the longest home winning streak in ACC history at 37 games when they take on the No. 10 North Carolina State Wolfpack on Saturday. The Tigers’ (4-0) last home loss was a 43-42 decision to Pittsburgh on Nov. 12, 2016. A win over the Wolfpack (4-0) would tie the ACC mark set by Florida State from 1992 to 2001. Miami’s FBS-record 58-game home winning streak from 1985 to 1994 predated the Hurricanes joining the ACC in 2004. Clemson leads the all-time series 59-29-1, including a 29-11-1 edge in games played at home.

Kickoff from Memorial Stadium in Clemson, S.C., is set for 7:30 p.m. ET. The Tigers are 7-point favorites in the latest NC State vs. Clemson odds from Caesars Sportsbook, while the over/under for total points scored is set at 43.5. Before making any North Carolina State vs. Clemson picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,100 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on NC State vs. Clemson and just locked in its picks and CFB predictions. You can visit SportsLine now to see the model’s picks. Here are the college football odds and betting lines for Clemson vs. NC State:

  • North Carolina State vs. Clemson spread: Clemson -7 
  • North Carolina State vs. Clemson over/under: 43.5 points 
  • North Carolina State vs. Clemson money line: North Carolina State +215, Clemson -267 
  • NCST: The Wolfpack are 5-2 against the spread in their last seven games against a team with a winning record 
  • CLEM: The Tigers are 20-9 ATS in their last 29 games after scoring more than 40 points in their previous game 
  • North Carolina State vs. Clemson picks: See picks here

Featured Game | Clemson Tigers vs. NC State Wolfpack

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