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Week 5 NFL picks, odds, 2022 best bets from advanced model: This five-way football parlay returns 25-1

Week 5 NFL picks, odds, 2022 best bets from advanced model: This five-way football parlay returns 25-1


Cleveland Browns running back Nick Chubb is well on his way to his fourth consecutive 1,000-yard season, as he ranks second with 459 yards through four games, four behind Saquon Barkley of the New York Giants. The 26-year-old Chubb already has recorded three 100-yard performances in 2022 after posting five in 14 contests last season. He will try to register his third straight triple-digit effort when Cleveland hosts the Los Angeles Chargers during the Week 5 NFL schedule. The Chargers are 2.5-point favorites in the Week 5 NFL odds at Caesars Sportsbook. Which Week 5 NFL lines should you target with your Week 5 NFL bets? Before you make any Week 5 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model.

The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 5 of the 2022 NFL season on an incredible 139-103 run on top-rated NFL picks that dates back to the 2017 season.  

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in five confident NFL best bets for Week 5. If you successfully parlay its picks, you’d be looking at a massive payout of around 25-1. You can only see the model’s Week 5 NFL picks at SportsLine

Top Week 5 NFL picks

After simulating every game 10,000 times, the model is high on the Miami Dolphins (-3.5) to win and cover against the New York Jets on Sunday. With Tua Tagovailoa on the shelf due to a concussion, Teddy Bridgewater will get the start at quarterback for the Dolphins, who are looking to rebound from the first defeat of the season. The 29-year-old Bridgewater is 42-21 against the spread as a starter, the best record among all QBs with at least 30 starts since 2000.

New York has lost both of its home games thus far this year, recording just one touchdown in the defeats, and has been swept by the Dolphins the last two season series. The Jets haven’t fared well against any AFC East rivals, as they’ve lost 12 consecutive division games. That is one reason the Dolphins are covering the spread in well over 50% of simulations. See which other NFL parlay picks to make here.

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