The Kansas City Chiefs (4-2) will travel to Levi’s Stadium to play the San Francisco 49ers (3-3) on Sunday. Both clubs were handed losses in Week 6. The Chiefs couldn’t outmatch the Buffalo Bills, falling 24-20. San Francisco went on the road to play the Atlanta Falcons, dropping that contest 28-14. The Niners made a splash on Thursday, acquiring two-time All-Pro running back Christian McCaffrey from the Carolina Panthers for several draft picks. McCaffrey could make his debut on Sunday, though the team hasn’t confirmed its plans yet.
Kickoff is set for 4:25 p.m. ET. Kansas City is a one-point favorite in the latest Chiefs vs. 49ers odds from Caesars Sportsbook, and the over/under is 49. Before making any 49ers vs. Chiefs picks, you need to check out the NFL predictions and betting advice from the SportsLine Projection Model.
The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 7 of the 2022 NFL season on an incredible 146-107 run on top-rated NFL picks that dates back to the 2017 season.
The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.
Now, the model has set its sights on Chiefs vs. Niners, and just locked in its picks and NFL predictions. You can visit SportsLine now to see the model’s picks. Here are the NFL odds and betting lines for Niners vs. Chiefs:
- Chiefs vs. 49ers spread: Kansas City -1
- Chiefs vs. 49ers over/under: 49 points
- Chiefs vs. 49ers money line: San Francisco +105, Kansas City -125
- KC: Over is 6-1 in Chiefs’ last seven road games
- SF: 49ers are 6-0 ATS versus teams with a winning record
- Chiefs vs. 49ers picks: See picks at SportsLine
Featured Game | San Francisco 49ers vs. Kansas City Chiefs
Why the Chiefs can cover
The Chiefs are ranked sixth in total offense (382.3) and fourth in passing yards per game (275.8)….
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