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NFL Thanksgiving best bets 2022: Top plays on point spread, totals and player props for holiday games

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If you’re looking for action to get you through the Thanksgiving holiday, you’re not alone. Betting on Thanksgiving football is probably my favorite part of the holiday. It’s a lot easier to talk to the family when you’re winning money at Caesars Sportsbook.  

We have a great slate to discuss this year. The Buffalo Bills pay a visit to the Detroit Lions, the New York Giants look to get back on track vs. the rival Dallas Cowboys and then the New England Patriots take on the Minnesota Vikings for our nightcap. It should be a fun day, and between spreads, Over/Unders and player props, there are plenty of opportunities to turn your Thanksgiving into a lucrative one. Let’s take a look at some bets we are high on. 

All NFL odds via Caesars Sportsbook  

Team records on Thanksgiving

Vikings 6-2
Patriots 3-2 
Cowboys 31-22-1 
Giants 7-5-3 
Bills 5-4-1 
Lions 37-43-2 

Bills (7-3) at Lions (4-6)

Thursday, 12:30 p.m. ET (CBS, Paramount+)

Featured Game | Detroit Lions vs. Buffalo Bills

Don’t look now, but the Lions are on a three-game win streak! Just three teams have scored 30 or more points in five games this season, and this matchup features two of them. The third is the Kansas City Chiefs. The Lions statistically have the No. 6 offense in the NFL (366.6 yards per game), but the defense is the worst in the NFL. Sill, Jared Goff and Co. and are coming off of a surprising 31-18 beatdown of the Giants last week. 

The Lions have lost five straight Thanksgiving games, and are 5-16 on the holiday over the past 21 years. Unfortunately for them, it looks like six straight losses on Thanksgiving are coming Thursday. The Bills have won two straight Thanksgiving games — including a 31-6 beatdown of the New Orleans Saints last year. Despite falling behind to the Cleveland Browns 10-3 in the second quarter last week, the Bills reeled off 25 unanswered points, and ended up defeating Cleveland by eight points. Interestingly enough, that game was played in Detroit as well due to a Buffalo snowstorm. 

Betting against the Lions on…

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