The No. 6 USC Trojans look to snap a losing streak to the No. 15 Notre Dame Fighting Irish on Saturday. Notre Dame has won the last four matchups in the rivalry, including a 31-16 win in South Bend in 2021. The 2022 edition will take place at Los Angeles Memorial Coliseum as the regular season finale for both teams. Notre Dame is 8-3 this season, including four wins in a row, and USC is 10-1 overall and 6-0 at home as the Trojans remain in the College Football Playoff hunt.
Caesars Sportsbook lists the Trojans as 4-point home favorites for this 7:30 p.m. ET kickoff. The total number of points Vegas thinks will be scored, or the over/under, is 63.5 in the latest Notre Dame vs. USC odds. Before making any USC vs. Notre Dame picks, be sure to check out the college football predictions and betting advice from SportsLine’s proven computer model.
The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.
Now, the model has set its sights on USC vs. Notre Dame and just revealed its picks and CFB predictions. You can visit SportsLine now to see the model’s picks. Now, here are several college football odds and trends for Notre Dame vs. USC:
- Notre Dame vs. USC spread: USC -4
- Notre Dame vs. USC over/under: 63.5 points
- Notre Dame vs. USC money line: USC -195, ND +162
- ND: The Irish are 6-5 against the spread this season
- USC: The Trojans are 7-4 against the spread this season
- Notre Dame vs. USC picks: See picks at SportsLine
Featured Game | USC Trojans vs. Notre Dame Fighting Irish
Why Notre Dame can cover
Notre Dame is playing incredibly well in recent days, winning eight of the last nine games. The Fighting Irish have won 19 straight games in November, the longest active streak in FBS, and Notre Dame blasted Boston College by a 44-0 margin last week. On offense, Notre Dame is averaging 39.8 points per game in the last five games and the Irish are putting up 34.4…
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