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Colts vs. Steelers odds, spread, line: Monday Night Football picks, NFL predictions from proven model

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Teams hoping to turn their fortunes around will meet when the Pittsburgh Steelers battle the Indianapolis Colts on Monday Night Football. The Steelers (3-7), who have not had a losing record since 2003 when they were 6-10, are coming off a 37-30 loss to the Cincinnati Bengals last week. The Colts (4-6-1), who finished 9-8 a year ago, are coming off a 17-16 loss to the Philadelphia Eagles. Indianapolis is 1-1 under interim coach Jeff Saturday.

Kickoff from Lucas Oil Stadium in Indianapolis is set for 8:15 p.m. ET. Indianapolis is a 2.5-point favorite in the latest Colts vs. Steelers odds from Caesars Sportsbook, while the over/under for total points scored is 39.5. Before locking in any Steelers vs. Colts picks or NFL bets, you have to check out the NFL predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 12 of the 2022 NFL season on an incredible 155-109 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has broken down Colts vs. Steelers on MNF. You can head to SportsLine to see the picks. Here are the NFL lines and trends for Steelers vs. Colts:

  • Colts vs. Steelers spread: Indianapolis -2.5
  • Colts vs. Steelers over/under: 39.5 points
  • Colts vs. Steelers money line: Steelers +118, Colts -140
  • PIT: Steelers are 6-2 against the spread in their last eight games following an ATS loss
  • IND: Colts are 7-3 ATS in their last 10 games following a straight-up loss
  • Colts vs. Steelers: See picks at SportsLine

Featured Game | Indianapolis Colts vs. Pittsburgh Steelers

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