One of the NFL’s best offenses will face one of the league’s best defenses when the Buffalo Bills visit the New England Patriots in a key Week 13 Thursday Night Football game at Gillette Stadium. The Bills (8-3) rank second in the league in total offense (415.9 yards per game). Meanwhile, the Patriots (6-5) are fourth in total defense (307.8 yards per game). Thursday’s game will be the first meeting between the teams since Buffalo routed New England, 47-17, in last season’s Wild Card round.
Kickoff is set for 8:15 p.m. ET. Buffalo is favored by four points in the latest Bills vs. Patriots odds from Caesars Sportsbook, and the over/under is 44. Before making any Patriots vs. Bills picks, be sure to check out the NFL predictions and betting advice from the SportsLine Projection Model.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 13 of the 2022 NFL season on an incredible 155-110 run on top-rated NFL picks that dates back to the 2017 season.
The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.
Now, the model has set its sights on Bills vs. Patriots and just locked in its picks and NFL TNF Week 13 predictions. You can visit SportsLine now to see the model’s picks. Here are the NFL odds and betting lines for Patriots vs. Bills:
- Bills vs. Patriots spread: Buffalo -4
- Bills vs. Patriots over/under: 44 points
- Bills vs. Patriots money line: Buffalo -215, New England +180
- BUF: Bills are 6-2 against the spread in their last eight games in December
- NE: Patriots are 4-0 ATS in their last four versus AFC opponents
- Bills vs. Patriots picks: See picks at SportsLine
Featured Game | New England Patriots vs. Buffalo Bills
Why the Bills can cover
Buffalo owns a potent and electric offense that can score plenty of points. The Bills roll into this divisional bout ranked second in the NFL in total offense (415.9), third in passing offense…
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