Tom Brady and the Tampa Bay Buccaneers (6-6) hit the road to take on Brock Purdy and the San Francisco 49ers (8-4) in a NFC matchup with significant postseason implications on Sunday at Levi’s Stadium. San Francisco is 5-1 at home, while the Buccaneers are 2-3 on the road. The Niners are turning to Purdy, the final selection in the 2022 NFL Draft, after Jimmy Garoppolo suffered a broken foot in the team’s 33-17 win over the Miami Dolphins in Week 13. The Bucs will be looking to build off their impressive 17-16 come from behind win over the New Orleans Saints on Monday Night Football. Tampa Bay is 3-8-1 against the spread, while San Francisco is 7-5 ATS in 2022.
Kickoff is at 4:25 p.m. ET. San Francisco is favored by 3.5 points in the latest 49ers vs. Buccaneers odds from Caesars Sportsbook, and the over/under is set at 37. Before making any Buccaneers vs. 49ers picks, you’ll want to see the NFL predictions and betting advice from the proven computer simulation model at SportsLine.
The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 14 of the 2022 NFL season on an incredible 156-112 run on top-rated NFL picks that dates back to the 2017 season. The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.
Now, the model has set its sights on 49ers vs. Bucs and just locked in its picks and NFL predictions. You can head to SportsLine now to see the model’s picks. Here are several NFL odds and betting lines for Bucs vs. Niners:
- 49ers vs. Buccaneers spread: 49ers -3.5
- 49ers vs. Buccaneers over/under: 37 points
- 49ers vs. Buccaneers money line: San Francisco -190, Tampa Bay +158
- 49ers vs. Buccaneers picks: See picks here
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