College Football

2022 Fenway Bowl prediction, odds, line: Louisville vs. Cincinnati picks, best bets from proven model

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The Louisville Cardinals and Cincinnati Bearcats resume their rivalry when they meet in the 2022 Fenway Bowl on Saturday. The clubs have met 53 times since 1929, with Cincinnati (9-3) owning a 30-22-1 advantage in the all-time series, but haven’t squared off since 2013. Louisville (7-5) has won 11 of the last 16 meetings, including the past two in overtime. The Cardinals ended their regular season with a 26-13 loss at Kentucky while the Bearcats dropped a 27-24 decision against Tulane in their finale. Former Louisville head coach Scott Satterfield has accepted the same position at Cincinnati, though he won’t be on either sideline for this one as both teams will be coached by an interim.Β 

Kickoff at Fenway Park in Boston is set for 11 a.m. ET. The Cardinals are 2-point favorites in the latest Louisville vs. Cincinnati odds from Caesars Sportsbook, while the over/under for total points scored is 38.5. Before locking in any Cincinnati vs. Louisville picks or Fenway Bowl 2022 predictions, be sure to check out what SportsLine’s advanced computer model has to say.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Louisville vs. Cincinnati and just locked in its Fenway Bowl 2022 picks and predictions. You can head to SportsLine now to see the model’s picks. Now, here are several college football odds and betting trends for Cincinnati vs. Louisville:

  • Louisville vs. Cincinnati spread: Cardinals -2
  • Louisville vs. Cincinnati over/under: 38.5 points
  • Louisville vs. Cincinnati money line: Cardinals -130, Bearcats +110
  • LOU: The Cardinals are 2-6 against the spread in their last eight neutral-site games
  • CIN: The Bearcats are 1-6-1 ATS in their last eight overall contests
  • Louisville vs. Cincinnati picks: See picks at SportsLine

Featured Game | Louisville Cardinals vs. Cincinnati Bearcats

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