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Saints vs. Panthers odds, line: 2023 NFL picks, Week 18 predictions from proven computer model

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The New Orleans Saints will try to extend their three-game winning streak when they face the Carolina Panthers on Sunday afternoon. New Orleans has put together a late-season surge, but it has been eliminated from playoff contention. Carolina is coming off a 30-24 loss at Tampa Bay and has been eliminated from the postseason as well.  

Kickoff is set for 1 p.m. ET. New Orleans is favored by 3.5 points in the latest Saints vs. Panthers odds from Caesars Sportsbook, while the over/under is set at 41.5. Before entering any Panthers vs. Saints picks, you’ll want to see the NFL predictions from the model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 18 of the 2022 NFL season on an incredible 160-113 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 14-6 roll on top-rated NFL picks since Week 7 of this season. 

The model ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Saints vs. Panthers. You can head to SportsLine to see its picks. Here are several NFL betting lines for Saints vs. Panthers:

  • Saints vs. Panthers spread: Saints -3.5
  • Saints vs. Panthers over/under: 42 points
  • Saints vs. Panthers money line: New Orleans -178, Carolina +150
  • Saints vs. Panthers picks: See picks here

Featured Game | New Orleans Saints vs. Carolina Panthers

Why the Saints can cover

New Orleans is quietly one of the hottest teams in the NFL heading into the final week of the regular season, even if it has already been eliminated from playoff contention. The Saints have notched three straight wins since a 17-16 loss to Tampa Bay on Dec. 5, beating the Falcons, Browns and Eagles in their last three games. They were 3.5-point road underdogs at Cleveland and were 4.5-point underdogs at Philadelphia last week. 

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