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Chiefs vs. 49ers prediction, odds, line, spread, time: 2024 Super Bowl picks from NFL model on 38-21 run

Chiefs vs. Bills odds, picks, how to watch, live stream, time: 2024 Divisional Round NFL expert prediction


The brightest stage in the sports world arrives on Sunday, Feb. 11 when the 2024 Super Bowl kicks off in Las Vegas. Patrick Mahomes, Travis Kelce and the Kansas City Chiefs will take on Brock Purdy, Christian McCaffrey and the San Francisco 49ers at Allegiant Stadium with a championship in the balance. The Niners are seeking a record-tying sixth Super Bowl victory in franchise history after earning the No. 1 seed in the NFL playoff bracket and defeating the Green Bay Packers and Detroit Lions in the postseason. The Chiefs are looking to earn back-to-back Super Bowl titles and knocked off the Miami Dolphins, Buffalo Bills and Baltimore Ravens in succession to reach Super Bowl 58.

Kickoff is at 6:30 p.m. ET in Las Vegas on CBS and Paramount+. San Francisco is a one-point favorite, while the over/under, or total number of points Vegas thinks will be scored, is 47.5 in the latest Chiefs vs. 49ers odds. Before locking in any 49ers vs. Chiefs picks, make sure you see the latest NFL predictions from SportsLine’s proven projection model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters the 2024 NFL Super Bowl on an incredible 184-129 run on top-rated NFL picks that dates back to the 2017 season. It also is on a 38-21 roll on top-rated picks since Week 7 of last season and nailed seven straight top-rated picks entering the 2024 NFL playoffs. 

The model ranked in the Top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Niners vs. Chiefs in Super Bowl 58. You can visit SportsLine now to see the picks. Here are the NFL odds and trends for Chiefs vs. Niners:

  • Chiefs vs. 49ers spread: 49ers -1
  • Chiefs vs. 49ers over/under: 47.5 points
  • Chiefs vs. 49ers money line: 49ers -118, Chiefs -102
  • SF: 49ers are 9-10 against the spread this season
  • KC: Chiefs are 12-7-1 against the spread this season
  • Chiefs vs. 49ers picks: See picks at SportsLine
  • Chiefs vs. 49ers streaming: Paramount+ (try free for seven days)

Why the 49ers can cover

The 49ers dominated the regular season, earning the No. 1 seed in the NFC and out-scoring opponents by 10.9 points per game. On defense, San Francisco is stout, but the team’s offense…

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