LSU vs. Mississippi State prediction, odds, line: College football picks, Week 3 best bets from proven model

The LSU Tigers and the Mississippi State Bulldogs are set to square off in an SEC matchup at 6 p.m. ET on Saturday at Tiger Stadium. The Tigers are 1-1 (1-0 at home) while MSU is 2-0 (1-0 on the road). LSU leads the all-time series with a 72-37-3 record and the Tigers won at Mississippi State last year by a 28-25 score.

The Bulldogs are favored by 2.5 points in the latest LSU vs. Mississippi State odds from Caesars Sportsbook, and the over/under is set at 53.5. Before entering any Mississippi State vs. LSU picks, you’ll want to see the college football predictions and betting advice from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,400 for $100 players on its top-rated college football picks against the spread. It enters Week 3 of the 2022 college football season on a 50-41 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on LSU vs. Mississippi State and just locked in its picks and CFB predictions. You can head to SportsLine to see its picks. Here are several college football odds and betting lines for Mississippi State vs. LSU:

• LSU vs. Mississippi State spread: LSU +2.5
• LSU vs. Mississippi State over/under: 53.5 points
• LSU vs. Mississippi State picks: See picks here

What you need to know about LSU

When you finish with 288 more yards than your opponent like LSU did on Saturday, a favorable outcome is almost sure to follow. It took its matchup at home with ease, bagging a 65-17 victory over the Southern University Jaguars. The game was pretty much decided by the half, when the score had already reached 51-0. LSU’s RB Armoni Goodwin looked sharp as he punched in two rushing touchdowns as part of an 85-yard rushing day.

Quarterback Jayden Daniels was highly efficient in completing 10-of-11…