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Week 4 NFL picks, odds, 2022 best bets from advanced model: This five-way football parlay would pay out 25-1

Week 4 NFL picks, odds, 2022 best bets from advanced model: This five-way football parlay would pay out 25-1


Despite being unbeaten through the first three weeks of the 2022 NFL schedule, the Miami Dolphins aren’t the most surprising team that hails from Florida. That distinction goes to the Jacksonville Jaguars, who sit atop the AFC South standings with a 2-1 record after going 3-14 last year. The Jaguars can prove they’re the real deal when they visit the undefeated Philadelphia Eagles (3-0) and come through for anyone taking them in their NFL predictions. Philadelphia is a 6.5-point favorite against Jacksonville in the latest Week 4 NFL odds at Caesars Sportsbook. Which Week 4 NFL lines should you target with your Week 4 NFL bets? Before you make any Week 4 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model.

The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 4 of the 2022 NFL season on an incredible 139-103 run on top-rated NFL picks that dates back to the 2017 season.  

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in five confident NFL best bets for Week 4. If you successfully parlay its picks, you’d be looking at a massive payout of around 25-1. You can only see the model’s Week 4 NFL picks at SportsLine

Top Week 4 NFL picks

After simulating every game 10,000 times, the model is high on the Pittsburgh Steelers (-3.5) to win and cover against the New York Jets on Sunday. The Steelers have dominated the all-time series, especially at home. Pittsburgh has won 18 of its 24 regular-season meetings with New York and is 8-1 on its own field, with the only loss being a 22-17 setback in 2010.

If not for a miraculous comeback in the final two minutes at Cleveland in Week 2, the Jets would be 0-3. They held their own statistically against Cincinnati last Sunday, but were unable to find the end zone, settling for four field goals in a 27-12 defeat at home. The model doesn’t expect New York to have much success this week, one reason Pittsburgh covers the spread in well over 50% of simulations. See which other NFL parlay picks to make here.

How to make Week 4 NFL parlays

The model also jumped on four…

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