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Colts vs. Cowboys odds, spread, line: Sunday Night Football picks, predictions by NFL model on 155-110 run

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The Dallas Cowboys are coming off back-to-back impressive performances and will look to continue that success when they take on the visiting Indianapolis Colts on Sunday Night Football. After crushing Minnesota 40-3, the Cowboys (8-3) followed that up with a 28-20 win over the New York Giants in a key battle between NFC East contenders. The Colts (4-7-1), however, have struggled mightily the past few weeks, including in a 24-17 home loss against Pittsburgh this past Monday night. Indianapolis, which is three games behind in the chase for the last Wild Card spot, has lost five of six, including two in a row.

Kickoff from AT&T Stadium in Arlington, Texas, is set for 8:20 p.m. ET. Dallas is a 10.5-point favorite in the latest Colts vs. Cowboys odds from Caesars Sportsbook, while the over/under for total points scored is 44.5. Before making any Cowboys vs. Colts picks, you need to check out the NFL predictions and betting advice from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 13 of the 2022 NFL season on an incredible 155-110 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Colts vs. Cowboys and just locked in his picks and NFL predictions. You can visit SportsLine now to see the model’s picks. Here are the NFL odds and betting lines and trends for Colts vs. Cowboys:

  • Colts vs. Cowboys spread: Dallas -10.5 
  • Colts vs. Cowboys over/under: 44.5 points 
  • Colts vs. Cowboys money line: Colts +430, Cowboys -600 
  • IND: Colts are 5-0 against the spread in their last five road games against teams with a winning home record 
  • DAL: Cowboys are 7-0 ATS in their last seven games in December 
  • Colts vs. Cowboys picks: See picks here

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