Los Angeles Chargers at Indianapolis Colts (Week 16) kicks off at 8:15 p.m. ET this Monday and is available to watch on ESPN and ESPN Deportes

The Indianapolis Colts will host the Los Angeles Chargers for their Week 16 matchup. The game time is set for 8:15 p.m. ET on Monday, Dec. 26, at Lucas Oil Stadium. The contest will mark the 28th all-time regular season contest between the teams, with the Chargers leading the series 17-10. In their last matchup, Indianapolis traveled to Los Angeles in Week 1 of 2019 and lost in overtime, 30-24.