Early in the season, NFL teams are still working out the kinks, but sometimes breakdowns on the field can result in big offensive plays. The potential for that is especially high in the 2022 NFL Kickoff Game on Thursday, making for plenty of tough decisions for your NFL DFS lineups. This year’s season-opener features a premier matchup between the Buffalo Bills and Los Angeles Rams, but which players from each team should you consider for your NFL DFS stacks? With so many playmakers on the field for both teams, there are plenty of talented options in the NFL DFS player pool. Which players are best suited to pick up Fantasy points from their NFL DFS matchups? Before setting your NFL DFS lineups for Rams vs. Bills on sites like DraftKings and FanDuel, be sure to check out the NFL DFS advice, strategy and stacks from SportsLine daily Fantasy expert Mike McClure.
McClure is a legendary professional DFS player with over $2 million in career winnings. His methodology has led to enormous cashes on FanDuel and DraftKings. He took down two high-stakes tournaments on FanDuel in 2020 and recorded a pair top-10 finishes in tournaments with over 130,000 entrants on DraftKings. His lineups also finished inside the top 1 percent in more than a dozen other tournaments.
He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine.
Now, McClure has turned his attention to Bills vs. Rams in the NFL Opening Kickoff Game and locked in his top daily Fantasy football picks. You can only see them by heading to SportsLine.
Top NFL DFS picks for Rams vs. Bills
One of McClure’s top NFL DFS picks for the NFL Kickoff Game is Rams receiver Cooper Kupp. Last season, he ran 87.5 percent of his routes out of the slot, and strong slot receivers were able to find success against Buffalo last year. Chris Godwin caught 10 passes for 105 yards in Tampa Bay’s 33-27 win over the Bills in Week 14. Mecole Hardman had nine receptions for 76 yards against Buffalo in Week 5.
Kupp’s talent supersedes the qualifier of calling him as a slot receiver, and Buffalo is likely to have Taron Johnson or Dane Jackson watching him depending on which side he lines up on. Against a team that Los Angeles could see again should it return to the Super…
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