College Football

USC vs. Washington State prediction, odds, line: College football picks, Week 6 best bets from proven model

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Caleb Williams and the No. 6 USC Trojans will be looking to keep their perfect season alive when they host the Washington State Cougars on Saturday night. USC has won four of its five games by double digits, including a 42-25 win over Arizona State last week. Washington State bounced back from its first loss of the season with a 28-9 win over California in Week 5. 

Kickoff is set for 7:30 p.m. ET. The Trojans are favored by 13 points in the latest USC vs. Washington State odds from Caesars Sportsbook, while the over/under is set at 66. Before entering any Washington State vs. USC picks, you’ll want to see the college football predictions and betting advice from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,100 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on USC vs. Washington State and just locked in its picks and CFB predictions. You can head to SportsLine to see its picks. Here are several college football odds and betting lines for USC vs. Washington State:

  • USC vs. Washington State spread: USC -13
  • USC vs. Washington State over/under: 66 points
  • USC vs. Washington State picks: See picks here

Featured Game | USC Trojans vs. Washington State Cougars

Why USC can cover

USC has not had any trouble winning games in blowout fashion this year, with four of its five wins coming by double digits. It is easy to cover big spreads with a dynamic offense, as the Trojans have scored at least 40 points in four of their five games. They are coming off a 42-25 win over Arizona State last week. 

Sophomore quarterback Caleb Williams has thrown for 1,402 yards, 12 touchdowns and just one interception while rushing for 144 yards and three touchdowns. Senior running back Travis Dye has balanced the offense with 422 rushing yards and five touchdowns on 62 carries, averaging…

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