Vilain is inactive in Minnesota’s first game since his NFL debut in Miami in Week 6.
Whitley was signed from Tennessee’s practice squad during the Vikings bye week.
Reed, Lowe and Otomewo are inactive for a seventh consecutive game.
Bullard was added to the injury report Friday because of an illness.
Defensive lineman Khyiris Tonga, who was signed from Atlanta’s practice squad on Oct. 4, is in position to make his Vikings debut.
Safety Theo Jackson is active for the first time after signing with Minnesota on Oct. 11.
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